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Skin microbiome-based therapies: perspectives and insights

Atualizado: 9 de out. de 2023

Skin-resident microorganisms are crucial in shaping and maintaining vital physiological processes. Their critical role includes modulating the host immune system and directly contributing to the integrity and functionality of the skin.

This review delves into the interactions between the skin microbiome and the host, shedding light on their roles in skin diseases. Also, it explores ongoing research into current therapeutic strategies that target the skin microbiome.

Here are some key insights:

1️⃣ Using antibiotics for the treatment of skin diseases suppresses pathogenic microbes, but prolonged use of these agents can lead to increased bacterial resistance

2️⃣ The skin microbiome plays a crucial role in the development of various skin diseases, making microbiota regulation a top strategy for treating skin diseases

3️⃣ Approaches to skin microbiome commercialization products or treatment pipelines can be divided into increasing the beneficial effects of microbes and suppressing harmful effects


Kim K et al. Recent advances in understanding the role of the skin microbiome in the treatment of atopic dermatitis. Exp Dermatol. 2023

About the author

Dr. Aline Santana is a Brazilian veterinarian with over 12 years of experience in both research and private dermatology practice. In 2021, she completed her PhD in veterinary dermatology at the University of São Paulo (Brazil), with a sandwich period at the University of Minnesota, where she conducted research on the skin microbiome of cats. Since 2012, she has been an active member of the Brazilian Society of Veterinary Dermatology (SBDV). From 2015 to 2021, Dr. Santana served as the director of social media marketing, contributing to the organization's outreach and communication efforts.




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