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Can the gut microbiome predict cancer immunotherapy response?

Can the gut microbiome predict cancer immunotherapy response?


Yes!


According to this study, advanced machine learning techniques can be utilized to predict responses to immunotherapy by analyzing gut microbiome data.


Key findings 

  • Specific bacterial taxa have been implicated in influencing the outcome of cancer immunotherapy.

  • The authors highlight the pivotal role of gut microorganisms in shaping immune responses.


Reference

Liang H, Jo JH, Zhang Z, MacGibeny MA, Han J, Proctor DM, Taylor ME, Che Y, Juneau P, Apolo AB, McCulloch JA, Davar D, Zarour HM, Dzutsev AK, Brownell I, Trinchieri G, Gulley JL, Kong HH. Predicting cancer immunotherapy response from gut microbiomes using machine learning models. Oncotarget. 2022


About the author  

Dr. Aline Santana is a Brazilian veterinarian with over 12 years of experience in both research and private dermatology practice. In 2021, she completed her PhD in veterinary dermatology at the University of São Paulo (Brazil), with a sandwich period at the University of Minnesota, where she conducted research on the skin microbiome of cats. Since 2012, she has been an active member of the Brazilian Society of Veterinary Dermatology (SBDV). From 2015 to 2021, Dr. Santana served as the director of social media marketing, contributing to the organization's outreach and communication efforts.

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