This retrospective study examines the prevalence of multidrug-resistant coagulase-positive staphylococci in canine and feline dermatological patients over a 10-year period.
Remarkably, the authors observed a significant shift in the antibiotic resistance pattern during this period. It is suggested that the disruption of the normal skin microbiota, induced by the use of broad-spectrum antibiotics, is a likely contributing factor to this phenomenon. Such disruption can lead to increased selection pressure, favoring the insurgence of antibiotic-resistant staphylococcal isolates.
Based on this data, the importance of preserving the diversity and functionality of the skin microbiota becomes even more evident. It is crucial to acknowledge that while broad-spectrum antibiotics target pathogens, they can also disturb commensal microbiota diversity. This dysbiosis can paradoxically increase susceptibility to infections.
Thus, in my opinion, microbiome-based therapies represent one of the most promising approaches to addressing the challenges posed by multidrug-resistant infections in veterinary dermatology.
Full article: https://lnkd.in/drUt8gRQ
About the author
Dr. Aline Santana is a Brazilian veterinarian with over 12 years of experience in both research and private dermatology practice. In 2021, she completed her PhD in veterinary dermatology at the University of São Paulo (Brazil), with a sandwich period at the University of Minnesota, where she conducted research on the skin microbiome of cats. Since 2012, she has been an active member of the Brazilian Society of Veterinary Dermatology (SBDV). From 2015 to 2021, Dr. Santana served as the director of social media marketing, contributing to the organization's outreach and communication efforts.
